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1

Skeletal Muscle PGC-1α1 Modulates Kynurenine Metabolism and Mediates Resilience to Stress-Induced Depression

Agudelo, Leandro Z., Femenía, Teresa, Orhan, Funda, Porsmyr-Palmertz, Margareta, Goiny, Michel, Martinez-Redondo, Vicente, Correia, Jorge C., Izadi, Manizheh, Bhat, Maria, Schuppe-Koistinen, Ina, Pett

Journal:

Year:

2014

Language:

english

File:

PDF, 3.82 MB

english, 2014

2

Metabolic fingerprinting of rat urine by LC/MS: Part 2. Data pretreatment methods for handling of complex data

Helena Idborg, Leila Zamani, Per-Olof Edlund, Ina Schuppe-Koistinen, Sven P. Jacobsson

Journal:

Journal of Chromatography B

Year:

2005

Language:

english

File:

PDF, 195 KB

english, 2005

3

Proof of principle of a generalized fuzzy Hough transform approach to peak alignment of one-dimensional1H NMR data

Leonard Csenki, Erik Alm, Ralf J. O. Torgrip, K. Magnus Åberg, Lars I. Nord, Ina Schuppe-Koistinen, Johan Lindberg

Journal:

Analytical and Bioanalytical Chemistry

Year:

2007

Language:

english

File:

PDF, 738 KB

english, 2007

4

What are the best reference values for a normal serum alanine transaminase activity (ALT)? Impact on the presumed prevalence of drug induced liver injury (DILI)

Helmi M’Kada, Mona Munteanu, Hugo Perazzo, Yen Ngo, Nittia Ramanujam, Françoise Imbert-Bismut, Vlad Ratziu, Dominique Bonnefont-Rousselot, Bernard Souberbielle, Ina Schuppe-Koistinen, Thierry Poynard

Journal:

Regulatory Toxicology and Pharmacology

Year:

2011

Language:

english

File:

PDF, 377 KB

english, 2011

5

Skeletal Muscle PGC-1α1 Modulates Kynurenine Metabolism and Mediates Resilience to Stress-Induced Depression

Agudelo, Leandro Z., Femenía, Teresa, Orhan, Funda, Porsmyr-Palmertz, Margareta, Goiny, Michel, Martinez-Redondo, Vicente, Correia, Jorge C., Izadi, Manizheh, Bhat, Maria, Schuppe-Koistinen, Ina, Pett

Journal:

Year:

2015

Language:

english

File:

PDF, 63 KB

english, 2015

6

Feature detection and alignment of hyphenated chromatographic–mass spectrometric data: Extraction of pure ion chromatograms using Kalman tracking

K. Magnus Åberg, Ralf J.O. Torgrip, Johan Kolmert, Ina Schuppe-Koistinen, Johan Lindberg

Journal:

Journal of Chromatography A

Year:

2008

Language:

english

File:

PDF, 1.22 MB

english, 2008

7

Metabolic fingerprinting of rat urine by LC/MS: Part 1. Analysis by hydrophilic interaction liquid chromatography–electrospray ionization mass spectrometry

Helena Idborg, Leila Zamani, Per-Olof Edlund, Ina Schuppe-Koistinen, Sven P. Jacobsson

Journal:

Journal of Chromatography B

Year:

2005

Language:

english

File:

PDF, 226 KB

english, 2005

8

Peak alignment of NMR signals by means of a genetic algorithm

Jenny Forshed, Ina Schuppe-Koistinen, Sven P. Jacobsson

Journal:

Analytica Chimica Acta

Year:

2003

Language:

english

File:

PDF, 240 KB

english, 2003

9

Molecular profiling of hepatotoxicity induced by a aminoguanidine carboxylate in the rat: gene expression profiling

Ina Schuppe-Koistinen, Anna-Lena Frisk, Lars Janzon

Journal:

Year:

2002

Language:

english

File:

PDF, 496 KB

english, 2002

10

A solution to the 1D NMR alignment problem using an extended generalized fuzzy Hough transform and mode support

Erik Alm, Ralf J. O. Torgrip, K. Magnus Åberg, Ina Schuppe-Koistinen, Johan Lindberg

Journal:

Analytical and Bioanalytical Chemistry

Year:

2009

Language:

english

File:

PDF, 718 KB

english, 2009

11

Time-resolved biomarker discovery in1H-NMR data using generalized fuzzy Hough transform alignment and parallel factor analysis

Erik Alm, Ralf J. O. Torgrip, K. Magnus Åberg, Ina Schuppe-Koistinen, Johan Lindberg

Journal:

Analytical and Bioanalytical Chemistry

Year:

2010

Language:

english

File:

PDF, 481 KB

english, 2010

12

A strategy for modelling dynamic responses in metabolic samples characterized by GC/MS

Pär Jonsson, Hans Stenlund, Thomas Moritz, Johan Trygg, Michael Sjöström, Elwin R. Verheij, Johan Lindberg, Ina Schuppe-Koistinen, Henrik Antti

Journal:

Year:

2006

Language:

english

File:

PDF, 414 KB

english, 2006

13

Statistical multivariate metabolite profiling for aiding biomarker pattern detection and mechanistic interpretations in GC/MS based metabolomics

Elin Pohjanen, Elin Thysell, Johan Lindberg, Ina Schuppe-Koistinen, Thomas Moritz, Pär Jonsson, Henrik Antti

Journal:

Year:

2006

Language:

english

File:

PDF, 494 KB

english, 2006

14

Standard reporting requirements for biological samples in metabolomics experiments: mammalian/in

Julian L. Griffin, Andrew W. Nicholls, Clare A. Daykin, Sarah Heald, Hector C. Keun, Ina Schuppe-Koistinen, John R. Griffiths, Leo L. Cheng, Philippe Rocca-Serra, Denis V. Rubtsov, Donald Robertson

Journal:

Year:

2007

Language:

english

File:

PDF, 366 KB

english, 2007

15

Predictive Metabolite Profiling Applying Hierarchical Multivariate Curve Resolution to GC−MS DataA Potential Tool for Multi-parametric Diagnosis

Jonsson, Pär, Johansson, Elin Sjövik, Wuolikainen, Anna, Lindberg, Johan, Schuppe-Koistinen, Ina, Kusano, Miyako, Sjöström, Michael, Trygg, Johan, Moritz, Thomas, Antti, Henrik

Journal:

Journal of Proteome Research

Year:

2006

Language:

english

File:

PDF, 409 KB

english, 2006

16

Differentiation of human hepatoma cells during confluence as revealed by gene expression profiling

Angelica Butura, Inger Johansson, Kerstin Nilsson, Lars Wärngård, Magnus Ingelman-Sundberg, Ina Schuppe-Koistinen

Journal:

Biochemical Pharmacology

Year:

2004

Language:

english

File:

PDF, 533 KB

english, 2004

17

Establishment of an HLA-typed cohort to elucidate the cellular and chemical basis of drug hypersensitivity reactions

Catherine Bell, Klara Martinsson, Lee Faulkner, Ana Alfirevic, Neil French, Jonathan Tugwood, Ina Schuppe-Koistinen, Karin Cederbrant, Munir Pirmohamed, Dean Naisbitt, B. Kevin Park

Journal:

Year:

2011

Language:

english

File:

PDF, 107 KB

english, 2011

18

S-Thiolation of human endothelial cell glyceraldehyde-3-phosphate dehydrogenase after hydrogen peroxide treatment

Ina SCHUPPE-KOISTINEN, Peter MOLDÉUS, Tomas BERGMAN, Ian A. COTGREAVE

Journal:

Year:

1994

Language:

english

File:

PDF, 534 KB

english, 1994

19

Studies on the Mechanism of Oxidative Modification of Human Glyceraldehyde-3-phosphate Dehydrogenase by Glutathione: Catalysis by Glutaredoxin

Christina Lind, Robert Gerdes, Ina Schuppe-Koistinen, Ian A. Cotgreave

Journal:

Biochemical and Biophysical Research Communications

Year:

1998

Language:

english

File:

PDF, 478 KB

english, 1998

20

The impact of CYP2E1 on the development of alcoholic liver disease as studied in a transgenic mouse model

Angelica Butura, Kerstin Nilsson, Kengathevy Morgan, Timothy R. Morgan, Samuel W. French, Inger Johansson, Ina Schuppe-Koistinen, Magnus Ingelman-Sundberg

Journal:

Journal of Hepatology

Year:

2009

Language:

english

File:

PDF, 668 KB

english, 2009

21

Safety biomarkers: Opportunities and challenges in drug discovery and development

Ina Schuppe-Koistinen

Journal:

Toxicology Letters

Year:

2012

Language:

english

File:

PDF, 42 KB

english, 2012

22

Isoform specific ALT measurement during liver and skeletal muscle damage

Björn Glinghammar, Ingalill Rafter, Ina Schuppe-Koistinen, Ian Cotgreave

Journal:

Toxicology Letters

Year:

2012

Language:

english

File:

PDF, 85 KB

english, 2012

23

Qualification of new biomarkers for drug-induced liver injury in a human cohort

Petra Thulin, Marcus Gry, Gunnar Nordahl, Getnet Yimer, Stig Linder, Eleni Aklillu, Björn Glinghammar, Ina Schuppe-Koistinen

Journal:

Toxicology Letters

Year:

2012

Language:

english

File:

PDF, 85 KB

english, 2012

24

Novel DILI biomarkers for prediction of acetaminophen-induced human hepatotoxicity

Jonas P. Bergström, Gry Marcus, Lengqvist Johan, Lindberg Johan, Schwenk Jochen, Nilsson Peter, Drobin Kimi, Paul B. Watkins, Schuppe Koistinen Ina

Journal:

Toxicology Letters

Year:

2012

Language:

english

File:

PDF, 90 KB

english, 2012

25

Identification of S-glutathionylated cellular proteins during oxidative stress and constitutive metabolism by affinity purification and proteomic analysis

Christina Lind, Robert Gerdes, Ylva Hamnell, Ina Schuppe-Koistinen, Helena Brockenhuus von Löwenhielm, Arne Holmgren, Ian A. Cotgreave

Journal:

Archives of Biochemistry and Biophysics

Year:

2002

Language:

english

File:

PDF, 224 KB

english, 2002

26

Gene and protein expression profiling of human cerebral endothelial cells activated with tumor necrosis factor-α

Bo Franzén, Kristina Duvefelt, Carina Jonsson, Britta Engelhardt, Jan Ottervald, Monica Wickman, Yang Yang, Ina Schuppe-Koistinen

Journal:

Molecular Brain Research

Year:

2003

Language:

english

File:

PDF, 1.43 MB

english, 2003

27

A role for γ-glutamyl transpeptidase in the transport of cystine into human endothelial cells: relationship to intracellular glutathione

Ian A. Cotgreave, Ina Schuppe-Koistinen

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Year:

1994

Language:

english

File:

PDF, 784 KB

english, 1994

28

The European IMI SAFE-T Consortium: Qualification of translational safety biomarkers

Frank Dieterle, Ina Schuppe-Koistinen, Neus Prats, Lauren Brown, Patrice Cacoub, Thierry Poynard, Joe Keenan, Thomas Krahn, Arno Kalkuhl, Ulf Neumann, Teresa Padro, Thomas Joos, Karin Briner, Jean-Mar

Journal:

Toxicology Letters

Year:

2009

Language:

english

File:

PDF, 83 KB

english, 2009

29

Identification of end points relevant to detection of potentially adverse drug reactions

Heike Hellmold, Charlotte B. Nilsson, Ina Schuppe-Koistinen, Kerstin Kenne, Lars Wärngård

Journal:

Toxicology Letters

Year:

2002

Language:

english

File:

PDF, 67 KB

english, 2002

30

Screening of Biomarkers in Rat Urine Using LC/Electrospray Ionization-MS and Two-Way Data Analysis

Idborg-Björkman, Helena, Edlund, Per-Olof, Kvalheim, Olav M., Schuppe-Koistinen, Ina, Jacobsson, Sven P.

Journal:

Analytical Chemistry

Year:

2003

Language:

english

File:

PDF, 269 KB

english, 2003

31

Plasma Profiling Reveals Human Fibulin-1 as Candidate Marker for Renal Impairment

Neiman, Maja, Hedberg, Jesper J., Dönnes, Pierre R., Schuppe-Koistinen, Ina, Hanschke, Stephan, Schindler, Ralf, Uhlén, Mathias, Schwenk, Jochen M., Nilsson, Peter

Journal:

Journal of Proteome Research

Year:

2011

Language:

english

File:

PDF, 3.06 MB

english, 2011

32

Analysis of Time-Related Metabolic Fluctuations Induced by Ethionine in the Rat

Skordi, Eleni, Yap, Ivan K. S., Claus, Sandrine P., Martin, François-Pierre J., Cloarec, Olivier, Lindberg, Johan, Schuppe-Koistinen, Ina, Holmes, Elaine, Nicholson, Jeremy K.

Journal:

Journal of Proteome Research

Year:

2007

Language:

english

File:

PDF, 1.32 MB

english, 2007

33

Second-Order Peak Detection for Multicomponent High-Resolution LC/MS Data

Stolt, Ragnar, Torgrip, Ralf J. O., Lindberg, Johan, Csenki, Leonard, Kolmert, Johan, Schuppe-Koistinen, Ina, Jacobsson, Sven P.

Journal:

Analytical Chemistry

Year:

2006

Language:

english

File:

PDF, 290 KB

english, 2006

34

Reliable Profile Detection in Comparative Metabolomics

Thysell, Elin, Pohjanen, Elin, Lindberg, Johan, Schuppe-Koistinen, Ina, Moritz, Thomas, Jonsson, Pär, Antti, Henrik

Journal:

Omics A Journal of Integrative Biology

Year:

2007

Language:

english

File:

PDF, 370 KB

english, 2007

35

Application of Dolichos biflorus in immunoassay detection of kidney collecting duct biomarkers

Sourial, Samer, Searchfield, Lydia, Schuppe-Koistinen, Ina, Betton, Graham R., Riccardi, Daniela, Price, Sally A.

Journal:

Year:

2010

Language:

english

File:

PDF, 1.58 MB

english, 2010

36

Reversible S-thiolation of Human Endothelial Cell Actin Accompanies a Structural Reorganisation of the Cytoskeleton

Schuppe-Koistinen, Ina, Moldéus, Peter, Bergman, Tomas, Cotgreave, Ian

Journal:

Year:

1995

Language:

english

File:

PDF, 1009 KB

english, 1995

37

Electroconvulsive therapy suppresses the neurotoxic branch of the kynurenine pathway in treatment-resistant depressed patients

Schwieler, Lilly, Samuelsson, Martin, Frye, Mark A., Bhat, Maria, Schuppe-Koistinen, Ina, Jungholm, Oscar, Johansson, Anette G., Landén, Mikael, Sellgren, Carl M., Erhardt, Sophie

Journal:

Journal of Neuroinflammation

Year:

2016

Language:

english

File:

PDF, 1001 KB

english, 2016

38

Genome-wide association and replication study of anti-tuberculosis drugs-induced liver toxicity

Petros, Zelalem, Lee, Ming-Ta Michael, Takahashi, Atsushi, Zhang, Yanfei, Yimer, Getnet, Habtewold, Abiy, Amogne, Wondwossen, Aderaye, Getachew, Schuppe-Koistinen, Ina, Mushiroda, Taisei, Makonnen, Ey

Journal:

Year:

2016

Language:

english

File:

PDF, 605 KB

english, 2016

39

Kynurenic acid and psychotic symptoms and personality traits in twins with psychiatric morbidity

Kegel, Magdalena E., Johansson, Viktoria, Wetterberg, Lennart, Bhat, Maria, Schwieler, Lilly, Cannon, Tyrone D., Schuppe-Koistinen, Ina, Engberg, Göran, Landén, Mikael, Hultman, Christina M., Erhardt,

Journal:

Psychiatry Research

Year:

2016

Language:

english

File:

PDF, 857 KB

english, 2016

40

Genome-Wide Association and Replication Study of Hepatotoxicity Induced by Antiretrovirals Alone or with Concomitant Anti-Tuberculosis Drugs

Petros, Zelalem, Lee, Ming Ta Michael, Takahashi, Atsushi, Zhang, Yanfei, Yimer, Getnet, Habtewold, Abiy, Schuppe-Koistinen, Ina, Mushiroda, Taisei, Makonnen, Eyasu, Kubo, Michiaki, Aklillu, Eleni

Journal:

Omics A Journal of Integrative Biology

Year:

2017

Language:

english

File:

PDF, 377 KB

english, 2017

41

Imbalanced Kynurenine Pathway in Schizophrenia

Kegel, Magdalena E., Bhat, Maria, Skogh, Elisabeth, Samuelsson, Martin, Lundberg, Kristina, Dahl, Marja-Liisa, Sellgren, Carl, Schwieler, Lilly, Engberg, Göran, Schuppe-Koistinen, Ina, Erhardt, Sophie

Journal:

International Journal of Tryptophan Research

Year:

2014

Language:

english

File:

PDF, 570 KB

english, 2014

42

Evaluation of Patterns of Liver Toxicity in Patients on Antiretroviral and Anti-Tuberculosis Drugs: A Prospective Four Arm Observational Study in Ethiopian Patients

Yimer, Getnet, Gry, Marcus, Amogne, Wondwossen, Makonnen, Eyasu, Habtewold, Abiy, Petros, Zelalem, Aderaye, Getachew, Schuppe-Koistinen, Ina, Lindquist, Lars, Aklillu, Eleni, Vermund, Sten H.

Journal:

Year:

2014

Language:

english

File:

PDF, 476 KB

english, 2014

43

Individual and stable autoantibody repertoires in healthy individuals

Neiman, Maja, Hellström, Cecilia, Just, David, Mattsson, Cecilia, Fagerberg, Linn, Schuppe-Koistinen, Ina, Gummesson, Anders, Bergström, Göran, Kallioniemi, Olli, Achour, Adnane, Sallinen, Riitta, Uhl

Journal:

Year:

2019

File:

PDF, 1.72 MB

2019

44

Individual and stable autoantibody repertoires in healthy individuals

Neiman, Maja, Hellström, Cecilia, Just, David, Mattsson, Cecilia, Fagerberg, Linn, Schuppe-Koistinen, Ina, Gummesson, Anders, Bergström, Göran, Kallioniemi, Olli, Achour, Adnane, Sallinen, Riitta, Uhl

Journal:

Year:

2019

Language:

english

File:

PDF, 1.72 MB

english, 2019

45

Molecular Profiling and Prediction of Toxicity

Schuppe-Koistinen, Ina

Journal:

Alternatives to laboratory animals : ATLA

Year:

2001

Language:

english

File:

PDF, 49 KB

english, 2001

46

Risk factors for poor neonatal outcome in pregnancies with decreased fetal movements

Sterpu, Irene, Pilo, Christina, Schuppe Koistinen, Ina, Lindqvist, Pelle G, GemzellâDanielsson, Kristina, Wiberg Itzel, Eva

Journal:

Acta Obstetricia et Gynecologica Scandinavica

Year:

2020

Language:

english

File:

PDF, 1.21 MB

english, 2020

47

The reproductive microbiome â clinical practice recommendations for fertility specialists

GarcÃa-Velasco, Juan A, Budding, Dries, Campe, Hartmut, Malfertheiner, Sara Fill, Hamamah, Samir, Santjohanser, Claudia, Schuppe-Koistinen, Ina, Nielsen, Henriette Svarre, Vieira-Silva, Sara, Laven,

Journal:

Reproductive BioMedicine Online

Year:

2020

File:

PDF, 581 KB

2020

48

Integration of molecular profiles in a longitudinal wellness profiling cohort

Tebani, Abdellah, Gummesson, Anders, Zhong, Wen, Koistinen, Ina Schuppe, Lakshmikanth, Tadepally, Olsson, Lisa M., Boulund, Fredrik, Neiman, Maja, Stenlund, Hans, HellstrÃ¶m, Cecilia, Karlsson, Max J.

Journal:

Nature Communications

Year:

2020

File:

PDF, 29.06 MB

2020

49

Facets of individual-specific health signatures determined from longitudinal plasma proteome profiling

Dodig-CrnkoviÄ, Tea, Hong, Mun-Gwan, Thomas, Cecilia Engel, HÃ¤ussler, Ragna S., Bendes, Annika, Dale, Matilda, Edfors, Fredrik, ForsstrÃ¶m, BjÃ¶rn, Magnusson, Patrik K.E., Schuppe-Koistinen, Ina, Od

Journal:

Year:

2020

File:

PDF, 3.33 MB

2020

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